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LS Life Sciences succeeded in mass extraction of the world’s highest purity ‘ginsenoside’ from ginseng

International patent application for mass production of 100% enzyme decomposition, extraction fermentation, and mass production for the first time in Korea and the world

LS Life Sciences announced on the 14th that it has applied for an international patent by successfully extracting the world’s highest purity low molecular weight ginsenosides (Ginsenosides, 668mg/g) in large quantities by using biotechnology to extract and ferment 100% of ginseng with enzymes for the first time in the world. said.

According to LS Life Sciences, ginsenoside, the most important component of ginseng and red ginseng, has a high molecular weight and is known to be difficult to extract active ingredients in large quantities.

Saponins present in various plants are found in the roots, stems, leaves, skins, and seeds of plants. In the past, they were known as non-nutritive substances. In addition to diabetes, hypertension and cholesterol lowering effects, various physiological activities were found.

Among them, ginseng saponin has a unique chemical structure different from saponin found in other plants. In particular, ginsenoside (saponin) is the main pharmacological action among various active ingredients of ginseng. Its pharmacological action and efficacy are also unique, so it is called ‘Ginsenoside’ in the meaning of Ginseng Glycoside. It is a word referring to saponin in ginseng and is used to distinguish it from saponins in other plants.

In particular, rare low-molecular-weight ginsenosides [Rare Ginsenosides Rg3, Rh1, Rh2, F2, CK, PPD, PPT, etc., various low-molecular-weight saponins, etc.] refer to ginsenosides that exist only in trace amounts in red ginseng, fermented ginseng, and wild ginseng. Compared to general saponin, it has a small size (low molecular weight) and relatively easy absorption into the body, and has excellent pharmacological activities such as immunity and anticancer.

However, existing ginseng and red ginseng products are sold at a high price as a red ginseng product when ginseng is steamed 1 or 2 times in a general and traditional way, or a black ginseng product called 'Gujunggupo' after steaming 9 times. It is known that there is a limit to extracting the side and the content is not much. In addition, although these products are absorbed in small amounts by the intestinal microflora, individual differences are large, so it is more efficient to take them in the form of low molecular weight ginsenosides in terms of absorption and bioavailability in the body.

LS Life Sciences CEO Na Hyun-joo said, “We are doing our best to realize love for neighbors, nature, and humanity through continuous research on the development of high-functional new materials from natural products.”

What are Ginsenosides?

Ginsenoside refers to saponin in ginseng, and saponin is a kind of chemically called glycoside. The name saponin is derived from the Greek word sapona, which means soap, and is named because it produces fine bubbles like soap in an aqueous solution.